I was fired from my job this past September. After filling out the OF-306, I received a call from my POC requesting additional information regarding my termination. My termination was a result of 3 suspensions. I emailed them the dates, reason, and duration of each suspension as well as my termination. 4 days later, they approved my OF-306 with a message stating "This one incident does not qualify as a pattern of employment misconduct in and of itself. Please proceed with his hiring action." So that's my experience, take it as you will.
Edit: My incident was classified as "Employment related misconduct - involving rule violation," which is listed as a Moderate Issue. However, there is another section labeled as "Evidence of dishonesty - falsification of application," which is listed as a Major & Substantial Issue.